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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM341072'
Target
Orexin receptor type 2
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM341072
(Benzyl trans-5-hydroxy-2-methylpiperidine-1-carbox...)
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Affinity Data
IC50: 8.30nM
Assay Description:
FLIPR Ca2+ Flux Assay (Okumura et al., Biochem. Biophys. Res. Comm. 280:976-981, 2001). In a typical experiment the OX1 and OX2 receptor antagonistic...
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Target Info
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Ligand Info
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Details
US Patent
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