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Found 2 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM50230147'
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50230147(CHEMBL4094071 | US10377763, Example 35)
Affinity DataKi:  725nMAssay Description:Antagonist activity at human OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular calcium level preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
University Of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50230147(CHEMBL4094071 | US10377763, Example 35)
Affinity DataIC50: >1.00E+4nMAssay Description:The Chinese hamster ovary (CHO) cell lines CHOOX1R and CHOOX2R were established by modifying CHO cells to constantly express the NFAT-luciferase gene...More data for this Ligand-Target Pair
In DepthDetails US Patent