BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 3' and Ligand = 'BDBM320240'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM320240
PNG
(3-(5-Methyl-1,3-thiazol-2-yl)-5-[2-oxa-5-azabicycl...)
Show SMILES C[C@@H](NC(=O)c1cc(OCC23CNC(CO2)C3)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F
Show InChI InChI=1S/C24H24F3N5O3S/c1-13-7-28-21(36-13)16-3-15(4-19(5-16)34-12-23-6-18(10-35-23)31-11-23)20(33)32-14(2)17-8-29-22(30-9-17)24(25,26)27/h3-5,7-9,14,18,31H,6,10-12H2,1-2H3,(H,32,33)/t14-,18?,23?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 15n/an/an/an/an/an/a



Bayer Aktiengesellschaft

US Patent


Assay Description
A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...


US Patent US10183937 (2019)


Article DOI: 10.1016/j.bmc.2006.07.028
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM320240
PNG
(3-(5-Methyl-1,3-thiazol-2-yl)-5-[2-oxa-5-azabicycl...)
Show SMILES C[C@@H](NC(=O)c1cc(OCC23CNC(CO2)C3)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F
Show InChI InChI=1S/C24H24F3N5O3S/c1-13-7-28-21(36-13)16-3-15(4-19(5-16)34-12-23-6-18(10-35-23)31-11-23)20(33)32-14(2)17-8-29-22(30-9-17)24(25,26)27/h3-5,7-9,14,18,31H,6,10-12H2,1-2H3,(H,32,33)/t14-,18?,23?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 15n/an/an/an/an/an/a



Bayer Aktiengesellschaft

US Patent


Assay Description
A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...


US Patent US10202369 (2019)


Article DOI: 10.1016/j.str.2004.10.004
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM320240
PNG
(3-(5-Methyl-1,3-thiazol-2-yl)-5-[2-oxa-5-azabicycl...)
Show SMILES C[C@@H](NC(=O)c1cc(OCC23CNC(CO2)C3)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F
Show InChI InChI=1S/C24H24F3N5O3S/c1-13-7-28-21(36-13)16-3-15(4-19(5-16)34-12-23-6-18(10-35-23)31-11-23)20(33)32-14(2)17-8-29-22(30-9-17)24(25,26)27/h3-5,7-9,14,18,31H,6,10-12H2,1-2H3,(H,32,33)/t14-,18?,23?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a 15n/an/an/an/an/an/a



BEYER AKTIENGESELLSCHAFT

US Patent


Assay Description
A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...


US Patent US10174016 (2019)


Article DOI: 10.1016/j.bmcl.2005.04.028
More data for this
Ligand-Target Pair