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Found 6 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM174780'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM174780(US10053462, 11 | US9102686, 11 | US9540388, 11)
Affinity DataKi:  398nM IC50:  5.69E+3nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM174780(US10053462, 11 | US9102686, 11 | US9540388, 11)
Affinity DataKi:  398nM IC50:  1.48E+4nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM174780(US10053462, 11 | US9102686, 11 | US9540388, 11)
Affinity DataIC50:  5.69E+3nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM174780(US10053462, 11 | US9102686, 11 | US9540388, 11)
Affinity DataIC50:  5.69E+3nMpH: 7.4Assay Description:Ca.sup.2+flux: 1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM174780(US10053462, 11 | US9102686, 11 | US9540388, 11)
Affinity DataIC50:  1.48E+4nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM174780(US10053462, 11 | US9102686, 11 | US9540388, 11)
Affinity DataIC50:  1.48E+4nMpH: 7.4Assay Description:Ca.sup.2+flux: 1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Me...More data for this Ligand-Target Pair
In DepthDetails US Patent