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Found 4 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM241720'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM241720(US9409917, 17 | US9409917, 18)
Affinity DataIC50:  1.30nMT: 2°CAssay Description:HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM241720(US9409917, 17 | US9409917, 18)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced calcium mobilization incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM241720(US9409917, 17 | US9409917, 18)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced calcium mobilization incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM241720(US9409917, 17 | US9409917, 18)
Affinity DataIC50:  1.60nMT: 2°CAssay Description:HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent