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Found 4 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM267212'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Axxam

US Patent
LigandPNGBDBM267212(2-chloro-N-[2-(3,3-difluoropiperidin-1-yl)-2-(4-me...)
Affinity DataIC50:  22nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Axxam

US Patent
LigandPNGBDBM267212(2-chloro-N-[2-(3,3-difluoropiperidin-1-yl)-2-(4-me...)
Affinity DataIC50:  22nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Axxam

US Patent
LigandPNGBDBM267212(2-chloro-N-[2-(3,3-difluoropiperidin-1-yl)-2-(4-me...)
Affinity DataIC50:  58nMAssay Description:YO-PROŽ-1 is a fluorescent DNA-binding dye with a MW of 374 Da (Molecular Probes, cat. Y3603). This method is based upon the presumed ability of YO-P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Axxam

US Patent
LigandPNGBDBM267212(2-chloro-N-[2-(3,3-difluoropiperidin-1-yl)-2-(4-me...)
Affinity DataIC50:  58nMAssay Description:YO-PROŽ-1 is a fluorescent DNA-binding dye with a MW of 374 Da (Molecular Probes, cat. Y3603). This method is based upon the presumed ability of YO-P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent