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Found 2 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM398158'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398158(4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-(oxe...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM398158(4-chloro-N-((4,4-difluorocyclohexyl)methyl)-1-(oxe...)
Affinity DataIC50:  55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent