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Found 4 Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase D' and Ligand = 'BDBM139995'
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM139995(US8901295, F428)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM139995(US8901295, F428)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity in absence of detergentMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM139995(US8901295, F428)
Affinity DataIC50:  6.20E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM139995(US8901295, F428)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed