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Found 4 Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor delta' and Ligand = 'BDBM50192837'
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50192837(CHEMBL3964816 | US10188627, Compound 8d)
Affinity DataEC50:  1.60nMAssay Description:Transactivation of ProLink tagged human PPARdelta transfected in CHO-K1 cells assessed as interaction with EA labelled SRCP after 3 to 16 hrs by beta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50192837(CHEMBL3964816 | US10188627, Compound 8d)
Affinity DataEC50:  7.40nMAssay Description:Cell Handling: PathHunter NHR cell lines were expanded from freezer stocks according to standard procedures. Cells were seeded in a total volume of 2...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50192837(CHEMBL3964816 | US10188627, Compound 8d)
Affinity DataEC50:  1.59nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50192837(CHEMBL3964816 | US10188627, Compound 8d)
Affinity DataEC50:  7.40nMAssay Description:Transactivation of human Gal4-PPARdelta LBD transfected in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed