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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase catalytic subunit type 3' and Ligand = 'BDBM346211'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3


(Homo sapiens (Human))
BDBM346211
PNG
(US10202373, Compound I-24 | US10202373, Example 6)
Show SMILES CCc1cc2c(cncc2n1S(=O)(=O)c1ccccc1)-c1ccnc(NC(C)=O)c1
Show InChI InChI=1S/C22H20N4O3S/c1-3-17-12-19-20(16-9-10-24-22(11-16)25-15(2)27)13-23-14-21(19)26(17)30(28,29)18-7-5-4-6-8-18/h4-14H,3H2,1-2H3,(H,24,25,27)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/an/an/a



MILLENNIUM PHARMACEUTICALS, INC.

US Patent


Assay Description
100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...


US Patent US10202373 (2019)

More data for this
Ligand-Target Pair