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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase catalytic subunit type 3' and Ligand = 'BDBM346235'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3


(Homo sapiens (Human))
BDBM346235
PNG
(US10202373, Compound I-49 | US10202373, Example 14)
Show SMILES O=S(=O)(C1CC1)n1ccc2c(cncc12)-c1ccnc(Nc2ccncn2)c1
Show InChI InChI=1S/C19H16N6O2S/c26-28(27,14-1-2-14)25-8-5-15-16(10-21-11-17(15)25)13-3-7-22-19(9-13)24-18-4-6-20-12-23-18/h3-12,14H,1-2H2,(H,20,22,23,24)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/an/an/a



MILLENNIUM PHARMACEUTICALS, INC.

US Patent


Assay Description
100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...


US Patent US10202373 (2019)

More data for this
Ligand-Target Pair