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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha' and Ligand = 'BDBM340326'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase regulatory subunit alpha


(Homo sapiens (Human))
BDBM340326
PNG
(US9758538, Example 14)
Show SMILES C[C@H]1COCCN1c1nc(cc(n1)-c1cnc(N)nc1)N(C)[C@]1(C)CCN(C1)C(=O)OC(C)(C)C
Show InChI InChI=1S/C24H36N8O3/c1-16-14-34-10-9-32(16)21-28-18(17-12-26-20(25)27-13-17)11-19(29-21)30(6)24(5)7-8-31(15-24)22(33)35-23(2,3)4/h11-13,16H,7-10,14-15H2,1-6H3,(H2,25,26,27)/t16-,24+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
1.07n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...


US Patent US9758538 (2017)

More data for this
Ligand-Target Pair