BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha' and Ligand = 'BDBM340396'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase regulatory subunit alpha


(Homo sapiens (Human))
BDBM340396
PNG
(US9758538, Example 84)
Show SMILES CN1CCCC(N2CC[C@@](CO)(C2)Nc2cc(nc(n2)N2CCOCC2)-c2cnc(N)nc2)C1=O
Show InChI InChI=1S/C23H33N9O3/c1-30-5-2-3-18(20(30)34)32-6-4-23(14-32,15-33)29-19-11-17(16-12-25-21(24)26-13-16)27-22(28-19)31-7-9-35-10-8-31/h11-13,18,33H,2-10,14-15H2,1H3,(H2,24,25,26)(H,27,28,29)/t18?,23-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
0.445n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85&#...


US Patent US9758538 (2017)

More data for this
Ligand-Target Pair