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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM261088'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM261088
PNG
(2-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]py...)
Show SMILES COc1c(cc(Cl)c(C)c1C1CN(CC(N)=O)C1)C(C)n1nc(C)c2c(N)ncnc12
Show InChI InChI=1S/C21H26ClN7O2/c1-10-15(22)5-14(19(31-4)17(10)13-6-28(7-13)8-16(23)30)12(3)29-21-18(11(2)27-29)20(24)25-9-26-21/h5,9,12-13H,6-8H2,1-4H3,(H2,23,30)(H2,24,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



Incyte Holdings Corporation; Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) was purchased from PerkinElmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...


US Patent US9730939 (2017)

More data for this
Ligand-Target Pair