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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM346185'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM346185
PNG
(WO2007/084786, Compound 17)
Show SMILES Nc1ncc(-c2cc(nc(n2)N2CCOCC2)N2CCCCC2=O)c(n1)C(F)(F)F
Show InChI InChI=1S/C18H20F3N7O2/c19-18(20,21)15-11(10-23-16(22)26-15)12-9-13(28-4-2-1-3-14(28)29)25-17(24-12)27-5-7-30-8-6-27/h9-10H,1-8H2,(H2,22,23,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 848n/an/an/an/an/an/a



Novartis AG

US Patent




US Patent US10202371 (2019)

More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Mus musculus (Mouse))
BDBM346185
PNG
(WO2007/084786, Compound 17)
Show SMILES Nc1ncc(-c2cc(nc(n2)N2CCOCC2)N2CCCCC2=O)c(n1)C(F)(F)F
Show InChI InChI=1S/C18H20F3N7O2/c19-18(20,21)15-11(10-23-16(22)26-15)12-9-13(28-4-2-1-3-14(28)29)25-17(24-12)27-5-7-30-8-6-27/h9-10H,1-8H2,(H2,22,23,26)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.04E+3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
AlphaScreen (Amplified Luminescent Proximity Homogeneous Assay, ALPHA, Perkin Elmer) is a non-radioactive bead-based proximity assay technology to st...


US Patent US10202371 (2019)

More data for this
Ligand-Target Pair