Found 8 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM50193013' TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human full-length His-tagged PI3K p110gamma expressed in baculovirus expression system using PIP2 as substrate measured aft...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human PI3Kgamma (S144 to A1102 residues) expressed in mammalian expression system incubated for 60 mins by ADAPTA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of PI3KCgamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of PI3Kgamma in human whole blood assessed as reduction in anti-IgE-stimulated CD63 expression in basophils preincubated for 30 mins follo...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kgamma expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of p110gamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of PI3Kgamma in human Raji cellsMore data for this Ligand-Target Pair
