BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 1A (PDE1A)' and Ligand = 'BDBM278986'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 1A (PDE1A)


(Homo sapiens (Human))
BDBM278986
PNG
(5-(2-ethoxypyridin-3-yl)-1-methyl-N-((1-methyl-1H-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cnn(C)c2)c2n(C)ncc2n1
Show InChI InChI=1S/C19H21N7O/c1-4-27-19-14(6-5-7-20-19)15-8-16(18-17(24-15)11-23-26(18)3)21-9-13-10-22-25(2)12-13/h5-8,10-12H,4,9H2,1-3H3,(H,21,24)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 670n/an/an/an/a7.625



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...


US Patent US10034861 (2018)

More data for this
Ligand-Target Pair