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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 1A (PDE1A)' and Ligand = 'BDBM278990'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 1A (PDE1A)


(Homo sapiens (Human))
BDBM278990
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N-(thiazol-2-yl...)
Show SMILES CCOc1ncccc1-c1cc(NCc2nccs2)c2n(ncc2n1)C(C)C
Show InChI InChI=1S/C20H22N6OS/c1-4-27-20-14(6-5-7-22-20)15-10-16(23-12-18-21-8-9-28-18)19-17(25-15)11-24-26(19)13(2)3/h5-11,13H,4,12H2,1-3H3,(H,23,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 520n/an/an/an/a7.625



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...


US Patent US10034861 (2018)

More data for this
Ligand-Target Pair