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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 1A (PDE1A)' and Ligand = 'BDBM278997'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 1A (PDE1A)


(Homo sapiens (Human))
BDBM278997
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1-methylpyrazo...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cnn(C)c2)c2n(nc(C)c2n1)C1COC1
Show InChI InChI=1S/C22H25N7O2/c1-4-31-22-17(6-5-7-23-22)18-8-19(24-9-15-10-25-28(3)11-15)21-20(26-18)14(2)27-29(21)16-12-30-13-16/h5-8,10-11,16H,4,9,12-13H2,1-3H3,(H,24,26)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 94n/an/an/an/a7.625



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...


US Patent US10034861 (2018)

More data for this
Ligand-Target Pair