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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 1A (PDE1A)' and Ligand = 'BDBM279167'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 1A (PDE1A)


(Homo sapiens (Human))
BDBM279167
PNG
(5-(2-(ethyl(methyl)amino)pyridin-3-yl)-1-isopropyl...)
Show SMILES CCN(C)c1ncccc1-c1cc(NCc2ccc(OC)cc2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C26H32N6O/c1-7-31(5)26-21(9-8-14-27-26)22-15-23(28-16-19-10-12-20(33-6)13-11-19)25-24(29-22)18(4)30-32(25)17(2)3/h8-15,17H,7,16H2,1-6H3,(H,28,29)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.10E+3n/an/an/an/a7.625



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...


US Patent US10034861 (2018)

More data for this
Ligand-Target Pair