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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 1A (PDE1A)' and Ligand = 'BDBM279169'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 1A (PDE1A)


(Homo sapiens (Human))
BDBM279169
PNG
(1-isopropyl-3-methyl-N-((1-methyl-1H-pyrazol-4-yl)...)
Show SMILES CC(C)n1nc(C)c2nc(cc(NCc3cnn(C)c3)c12)-c1ocnc1C
Show InChI InChI=1S/C19H23N7O/c1-11(2)26-18-15(20-7-14-8-22-25(5)9-14)6-16(19-13(4)21-10-27-19)23-17(18)12(3)24-26/h6,8-11H,7H2,1-5H3,(H,20,23)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 98n/an/an/an/a7.625



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...


US Patent US10034861 (2018)

More data for this
Ligand-Target Pair