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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 1A (PDE1A)' and Ligand = 'BDBM279170'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 1A (PDE1A)


(Homo sapiens (Human))
BDBM279170
PNG
(5-[2-(dimethylamino)-3-pyridyl]-1-isopropyl-3-meth...)
Show SMILES CC(C)n1nc(C)c2nc(cc(NCc3cnn(C)c3)c12)-c1cccnc1N(C)C
Show InChI InChI=1S/C22H28N8/c1-14(2)30-21-19(24-11-16-12-25-29(6)13-16)10-18(26-20(21)15(3)27-30)17-8-7-9-23-22(17)28(4)5/h7-10,12-14H,11H2,1-6H3,(H,24,26)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.10E+3n/an/an/an/a7.625



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...


US Patent US10034861 (2018)

More data for this
Ligand-Target Pair