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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 1C (PDE1C)' and Ligand = 'BDBM278983'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 1C (PDE1C)


(Homo sapiens (Human))
BDBM278983
PNG
(5-(2-ethoxy-3-pyridyl)-N-[(1-methylpyrazol-4-yl)me...)
Show SMILES CCCn1ncc2nc(cc(NCc3cnn(C)c3)c12)-c1cccnc1OCC
Show InChI InChI=1S/C21H25N7O/c1-4-9-28-20-18(23-11-15-12-24-27(3)14-15)10-17(26-19(20)13-25-28)16-7-6-8-22-21(16)29-5-2/h6-8,10,12-14H,4-5,9,11H2,1-3H3,(H,23,26)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 340n/an/an/an/a7.625



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...


US Patent US10034861 (2018)

More data for this
Ligand-Target Pair