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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 1C (PDE1C)' and Ligand = 'BDBM278998'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 1C (PDE1C)


(Homo sapiens (Human))
BDBM278998
PNG
(5-(2-ethoxy-3-pyridyl)-1,3-dimethyl-N-[(1-methylpy...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cnn(C)c2)c2n(C)nc(C)c2n1
Show InChI InChI=1S/C20H23N7O/c1-5-28-20-15(7-6-8-21-20)16-9-17(22-10-14-11-23-26(3)12-14)19-18(24-16)13(2)25-27(19)4/h6-9,11-12H,5,10H2,1-4H3,(H,22,24)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.90E+3n/an/an/an/a7.625



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...


US Patent US10034861 (2018)

More data for this
Ligand-Target Pair