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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 1C (PDE1C)' and Ligand = 'BDBM279010'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 1C (PDE1C)


(Homo sapiens (Human))
BDBM279010
PNG
(5-(2-ethoxy-3-pyridyl)-N-(1H-imidazol-4-ylmethyl)-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2c[nH]cn2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C21H25N7O/c1-5-29-21-16(7-6-8-23-21)17-9-18(24-11-15-10-22-12-25-15)20-19(26-17)14(4)27-28(20)13(2)3/h6-10,12-13H,5,11H2,1-4H3,(H,22,25)(H,24,26)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 32n/an/an/an/a7.625



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...


US Patent US10034861 (2018)

More data for this
Ligand-Target Pair