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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 1C (PDE1C)' and Ligand = 'BDBM279066'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 1C (PDE1C)


(Homo sapiens (Human))
BDBM279066
PNG
(5-(2-isopropoxy-3-pyridyl)-1-isopropyl-3-methyl-N-...)
Show SMILES CC(C)Oc1ncccc1-c1cc(NCc2cnn(C)c2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C23H29N7O/c1-14(2)30-22-20(25-11-17-12-26-29(6)13-17)10-19(27-21(22)16(5)28-30)18-8-7-9-24-23(18)31-15(3)4/h7-10,12-15H,11H2,1-6H3,(H,25,27)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 9.10n/an/an/an/a7.625



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...


US Patent US10034861 (2018)

More data for this
Ligand-Target Pair