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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 4B2' and Ligand = 'BDBM325698'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 4B2


(Homo sapiens (Human))
BDBM325698
PNG
(US9636336, Example 99 | [(1S)-2-(3,5-dichloro-1-ox...)
Show SMILES COc1ccc(cc1OC)[C@H](Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNC(C(=O)OC[C@@H]2CCCCN2C)c2ccccc2)s1
Show InChI InChI=1S/C36H39Cl2N3O7S/c1-40-16-8-7-11-25(40)22-47-36(43)34(23-9-5-4-6-10-23)39-19-26-13-15-33(49-26)35(42)48-31(18-27-28(37)20-41(44)21-29(27)38)24-12-14-30(45-2)32(17-24)46-3/h4-6,9-10,12-15,17,20-21,25,31,34,39H,7-8,11,16,18-19,22H2,1-3H3/t25-,31-,34?/m0/s1
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<1n/an/an/an/an/an/a



CHIESI FARMACEUTICI S.p.A.

US Patent


Assay Description
PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...


US Patent US9636336 (2017)

More data for this
Ligand-Target Pair