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Found 3 Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM108110'
TargetPlasma kallikrein(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM108110(US8598206, Table 6, 19)
Affinity DataKi:  1.5nMAssay Description:The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM108110(US8598206, Table 6, 19)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human plasma kallikrein using S2302 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM108110(US8598206, Table 6, 19)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human t-PA was determined by the method described in [0092]-[0098] using recombinant human tissue-type plasminogen activator (Actilyse&...More data for this Ligand-Target Pair
In DepthDetails US Patent