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Found 2 Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM108118'
TargetPlasma kallikrein(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM108118(US8598206, Table 6, 1)
Affinity DataKi:  5.30nMAssay Description:The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM108118(US8598206, Table 6, 1)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human t-PA was determined by the method described in [0092]-[0098] using recombinant human tissue-type plasminogen activator (Actilyse&...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent