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Found 3 Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM247418'
TargetPlasma kallikrein(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM247418(US10336754, Example 372 | US11053247, Example 372 ...)
Affinity DataKi:  35nM ΔG°:  -44.3kJ/molepH: 7.5 T: 2°CAssay Description:Plasma kallikrein determinations were made in 0.1 M sodium phosphate buffer at a pH of 7.5 containing 0.1-0.2 M sodium chloride and 0.5% PEG 8000. De...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM247418(US10336754, Example 372 | US11053247, Example 372 ...)
Affinity DataKi:  35nMAssay Description:Plasma kallikrein determinations were made in 0.1 M sodium phosphate buffer at a pH of 7.5 containing 0.1-0.2 M sodium chloride and 0.5% PEG 8000. De...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM247418(US10336754, Example 372 | US11053247, Example 372 ...)
Affinity DataKi:  35nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent