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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM335741'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Plasma kallikrein


(Homo sapiens (Human))
BDBM335741
PNG
((4-Aminomethyl-2-methyl-benzyl)-[1-(2-phenyl-thiaz...)
Show SMILES Cc1cc(CN)ccc1CNc1nccc2n(Cc3csc(n3)-c3ccccc3)ccc12
Show InChI InChI=1S/C26H25N5S/c1-18-13-19(14-27)7-8-21(18)15-29-25-23-10-12-31(24(23)9-11-28-25)16-22-17-32-26(30-22)20-5-3-2-4-6-20/h2-13,17H,14-16,27H2,1H3,(H,28,29)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.59E+3n/an/an/an/an/an/a



Kalvista Pharmaceuticals Limited

US Patent


Assay Description
Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...


US Patent US9738641 (2017)

More data for this
Ligand-Target Pair