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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor subunit B (PDGFB)' and Ligand = 'BDBM234582'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor subunit B (PDGFB)


(Homo sapiens (Human))
BDBM234582
PNG
(US9353093, 4)
Show SMILES CC(C)c1cccc(NC(=O)Nc2ccc(cc2)-c2cc3ccccc3n2C(N)=O)c1
Show InChI InChI=1S/C25H24N4O2/c1-16(2)18-7-5-8-21(14-18)28-25(31)27-20-12-10-17(11-13-20)23-15-19-6-3-4-9-22(19)29(23)24(26)30/h3-16H,1-2H3,(H2,26,30)(H2,27,28,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 16n/an/an/an/a7.4n/a



Allergan, Inc.

US Patent


Assay Description
Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...


US Patent US9353093 (2016)


BindingDB Entry DOI: 10.7270/Q2BZ64ZV
More data for this
Ligand-Target Pair