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Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor subunit B (PDGFB)' and Ligand = 'BDBM234583'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor subunit B (PDGFB)


(Homo sapiens (Human))
BDBM234583
PNG
(US9353093, 5)
Show SMILES NC(=O)n1c(cc2ccccc12)-c1ccc(NC(=O)Nc2ccc(F)c(Cl)c2)cc1
Show InChI InChI=1S/C22H16ClFN4O2/c23-17-12-16(9-10-18(17)24)27-22(30)26-15-7-5-13(6-8-15)20-11-14-3-1-2-4-19(14)28(20)21(25)29/h1-12H,(H2,25,29)(H2,26,27,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 19n/an/an/an/a7.4n/a



Allergan, Inc.

US Patent


Assay Description
Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...


US Patent US9353093 (2016)


BindingDB Entry DOI: 10.7270/Q2BZ64ZV
More data for this
Ligand-Target Pair