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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor subunit B (PDGFB)' and Ligand = 'BDBM234588'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor subunit B (PDGFB)


(Homo sapiens (Human))
BDBM234588
PNG
(US9353093, 10)
Show SMILES NC(=O)n1c(cc2ccccc12)-c1ccc(NC(=O)Nc2ccccc2)cc1
Show InChI InChI=1S/C22H18N4O2/c23-21(27)26-19-9-5-4-6-16(19)14-20(26)15-10-12-18(13-11-15)25-22(28)24-17-7-2-1-3-8-17/h1-14H,(H2,23,27)(H2,24,25,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 23n/an/an/an/a7.4n/a



Allergan, Inc.

US Patent


Assay Description
Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...


US Patent US9353093 (2016)


BindingDB Entry DOI: 10.7270/Q2BZ64ZV
More data for this
Ligand-Target Pair