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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor subunit B (PDGFB)' and Ligand = 'BDBM234602'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor subunit B (PDGFB)


(Homo sapiens (Human))
BDBM234602
PNG
(US9353093, 31)
Show SMILES NC(=O)n1c(cc2ccccc12)-c1cc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cs1
Show InChI InChI=1S/C21H14ClF3N4O2S/c22-15-6-5-12(8-14(15)21(23,24)25)27-20(31)28-13-9-18(32-10-13)17-7-11-3-1-2-4-16(11)29(17)19(26)30/h1-10H,(H2,26,30)(H2,27,28,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 151n/an/an/an/a7.4n/a



Allergan, Inc.

US Patent


Assay Description
Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...


US Patent US9353093 (2016)


BindingDB Entry DOI: 10.7270/Q2BZ64ZV
More data for this
Ligand-Target Pair