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Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor subunit B (PDGFB)' and Ligand = 'BDBM234604'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor subunit B (PDGFB)


(Homo sapiens (Human))
BDBM234604
PNG
(US9353093, 33)
Show SMILES Cc1ccc(F)c(c1)C(=O)Nc1csc(c1)-c1cc2ccccc2n1C(N)=O
Show InChI InChI=1S/C21H16FN3O2S/c1-12-6-7-16(22)15(8-12)20(26)24-14-10-19(28-11-14)18-9-13-4-2-3-5-17(13)25(18)21(23)27/h2-11H,1H3,(H2,23,27)(H,24,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/a7.4n/a



Allergan, Inc.

US Patent


Assay Description
Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...


US Patent US9353093 (2016)


BindingDB Entry DOI: 10.7270/Q2BZ64ZV
More data for this
Ligand-Target Pair