Found 7 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 2' and Ligand = 'BDBM50084621'
Affinity DataKi: 0.850nMAssay Description:Inhibition of human PARP2 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of PARP2 (unknown origin) after 1 min in presence of NAD by top count analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PARP2 (unknown origin) using NAD as substrate incubated for 1 minMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged human PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells using histone mixture (H2A and H2B) a...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant N-terminal Avi-6His-TEV tagged PARP2 full length expressed in pFastBac expression system incubated for 4 hrs by fluor...More data for this Ligand-Target Pair
Affinity DataKd: 3.30nMAssay Description:Binding affinity to PARP2 (unknown origin) assessed as apparent dissociation constantMore data for this Ligand-Target Pair