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Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium channel protein TASK-1' and Ligand = 'BDBM218279'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium channel protein TASK-1


(Homo sapiens (Human))
BDBM218279
PNG
(US9284333, 16t)
Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1c(F)cccc1F
Show InChI InChI=1/C23H27F2N3O3/c1-3-18(21-16(24)7-4-8-17(21)25)26-22(29)15-12-19(28-10-11-31-13-20(15)28)23(30)27-9-5-6-14(27)2/h4,7-8,12,14,18H,3,5-6,9-11,13H2,1-2H3,(H,26,29)/t14-,18+/s2
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 44n/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...


US Patent US9284333 (2016)

More data for this
Ligand-Target Pair