BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50193853'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50193853
PNG
((R)-4-(5-chloro-1H-indole-2-sulfonyl)-1-[4-(N,N-di...)
Show SMILES CN(C)C(=N)c1ccc(CN2[C@H](CN(CC2=O)S(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)C(O)=O)cc1
Show InChI InChI=1S/C23H24ClN5O5S/c1-27(2)22(25)15-5-3-14(4-6-15)11-29-19(23(31)32)12-28(13-21(29)30)35(33,34)20-10-16-9-17(24)7-8-18(16)26-20/h3-10,19,25-26H,11-13H2,1-2H3,(H,31,32)/t19-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Portola Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cells


Bioorg Med Chem Lett 16: 5507-12 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.039
BindingDB Entry DOI: 10.7270/Q2SF2X05
More data for this
Ligand-Target Pair