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Found 3 Enz. Inhib. hit(s) with Target = 'Probable G-protein coupled receptor 139' and Ligand = 'BDBM263489'
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM263489((s)-2-(6-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...)
Affinity DataKi:  128nM ΔG°:  -36.6kJ/molepH: 7.4 T: 2°CAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM263489((s)-2-(6-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...)
Affinity DataKi:  128nMAssay Description:Membranes were removed from −80° C., thawed and diluted in cold radioligand assay buffer (20 mM HEPES pH 7.4/5 mM MgCl2/1 mM CaCl2/Roche protea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM263489((s)-2-(6-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...)
Affinity DataKi:  1.28E+5nMAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent