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Found 11 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50393843'
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataKi:  23nMAssay Description:Inhibition of human POP expressed in Escherichia coli BL21 pre-incubated for 30 mins before ZGP-pNA substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of second step of inhibition pre-incubated for 2 hrs before addition of ZGP-pNA sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  45nMAssay Description:Inhibition of POP in human HCEC cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  45nMAssay Description:Inhibition of POP in human LN229 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  45nMAssay Description:Inhibition of POP in human LNZ308 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  81nMAssay Description:Inhibition of POP in human LN18 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  200nMAssay Description:Inhibition of POP in intact human LNZ308 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  300nMAssay Description:Inhibition of POP in intact human LN18 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  450nMAssay Description:Inhibition of POP in intact human LN229 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  500nMAssay Description:Inhibition of POP in intact human HCEC cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed