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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP2 subtype' and Ligand = 'BDBM263358'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM263358
PNG
(US9546162, 16)
Show SMILES COc1cccc(CCN2CCc3cccc(CCc4ccc(cc4)C(O)=O)c23)c1
Show InChI InChI=1S/C26H27NO3/c1-30-24-7-2-4-20(18-24)14-16-27-17-15-22-6-3-5-21(25(22)27)11-8-19-9-12-23(13-10-19)26(28)29/h2-7,9-10,12-13,18H,8,11,14-17H2,1H3,(H,28,29)
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
41n/an/an/an/an/an/a7.4n/a



ALLERGAN, INC.

US Patent


Assay Description
Cells were seeded at a density of 5×104 cells per well in Biocoat® Poly-D-lysine-coated black-wall, clear-bottom 96-well plates (Becton-Dickinson) an...


US Patent US9546162 (2017)

More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM263358
PNG
(US9546162, 16)
Show SMILES COc1cccc(CCN2CCc3cccc(CCc4ccc(cc4)C(O)=O)c23)c1
Show InChI InChI=1S/C26H27NO3/c1-30-24-7-2-4-20(18-24)14-16-27-17-15-22-6-3-5-21(25(22)27)11-8-19-9-12-23(13-10-19)26(28)29/h2-7,9-10,12-13,18H,8,11,14-17H2,1H3,(H,28,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.70E+3n/an/an/an/an/an/a7.4n/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...


US Patent US9546162 (2017)

More data for this
Ligand-Target Pair