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Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM261794'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM261794(9-Ethyl-3-[1-(2-methoxyethyl)-5-(1H-tetrazol-5-yl)...)
Affinity DataIC50:  6.80nMAssay Description:Antagonist activity at human EP4R assessed as inhibition of agonist-induced cAMP production by fluorescent cAMP tracer cAMP-d2 based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM261794(9-Ethyl-3-[1-(2-methoxyethyl)-5-(1H-tetrazol-5-yl)...)
Affinity DataIC50:  13.4nMT: 2°CAssay Description:4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent