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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase (cyclooxygenase)' and Ligand = 'BDBM173525'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM173525
PNG
(1-(4-Aminosulfonylphenyl)-3-(p-tolyl)-5-(4-trifluo...)
Show SMILES Cc1ccc(cc1)-c1cc(-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C23H18F3N3O2S/c1-15-2-4-16(5-3-15)21-14-22(17-6-8-18(9-7-17)23(24,25)26)29(28-21)19-10-12-20(13-11-19)32(27,30)31/h2-14H,1H3,(H2,27,30,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.81E+4n/an/an/an/an/an/a



Beni-Suef University



Assay Description
The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...


Bioorg Chem 63: 13-23 (2015)


Article DOI: 10.1016/j.bioorg.2015.09.002
BindingDB Entry DOI: 10.7270/Q28G8JGV
More data for this
Ligand-Target Pair