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Found 4 Enz. Inhib. hit(s) with Target = 'Protein O-GlcNAcase' and Ligand = 'BDBM205428'
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics

US Patent
LigandPNGBDBM205428(US9243020, 33 | US9815861, Example 33)
Affinity DataKi:  13nM ΔG°:  -45.0kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics

US Patent
LigandPNGBDBM205428(US9243020, 33 | US9815861, Example 33)
Affinity DataKi:  13nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics

US Patent
LigandPNGBDBM205428(US9243020, 33 | US9815861, Example 33)
Affinity DataKi:  23nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein O-GlcNAcase(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM205428(US9243020, 33 | US9815861, Example 33)
Affinity DataEC50:  58nMAssay Description:Inhibition of OGA in rat PC12 cells assessed as OGlcNAcylated protein level incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed