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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein lysine methyltransferase SUV4-20H1 (SUV4-20H1)' and Ligand = 'BDBM223979'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein lysine methyltransferase SUV4-20H1 (SUV4-20H1)


(Homo sapiens (Human))
BDBM223979
PNG
(7-Chloro-N-cyclopentylquinolin-4-amine (1))
Show SMILES Clc1ccc2c(NC3CCCC3)ccnc2c1
Show InChI InChI=1S/C14H15ClN2/c15-10-5-6-12-13(7-8-16-14(12)9-10)17-11-3-1-2-4-11/h5-9,11H,1-4H2,(H,16,17)
PDB

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.90E+3n/an/an/an/a8.025



AbbVie



Assay Description
Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...


Nat Chem Biol 13: 317-324 (2017)


Article DOI: 10.1038/nchembio.2282
BindingDB Entry DOI: 10.7270/Q2X065XF
More data for this
Ligand-Target Pair