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Found 4 Enz. Inhib. hit(s) with Target = 'Protein-glutamine gamma-glutamyltransferase 2' and Ligand = 'BDBM50420459'
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50420459(CHEMBL2086528)
Affinity DataIC50:  10nMAssay Description:Ability to inhibit U-46,619-induced contraction of isolated strips of rabbit thoracic aorta, which is the measure of thromboxane receptor antagonismMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50420459(CHEMBL2086528)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Mus musculus)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50420459(CHEMBL2086528)
Affinity DataIC50:  16nMAssay Description:Inhibition of mouse recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50420459(CHEMBL2086528)
Affinity DataIC50:  770nMAssay Description:Inhibition of human TG2 in HEK cells by fluorescent transamidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed