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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-serine O-palmitoleoyltransferase porcupine' and Ligand = 'BDBM50125940'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-serine O-palmitoleoyltransferase porcupine


(Homo sapiens)
BDBM50125940
PNG
(CHEMBL3623876)
Show SMILES Cc1cc(ccn1)-c1cccc(OCC(=O)Nc2ccc(cn2)-c2cnccn2)c1
Show InChI InChI=1S/C23H19N5O2/c1-16-11-18(7-8-25-16)17-3-2-4-20(12-17)30-15-23(29)28-22-6-5-19(13-27-22)21-14-24-9-10-26-21/h2-14H,15H2,1H3,(H,27,28,29)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 188n/an/an/an/an/an/a



Soochow University

Curated by ChEMBL


Assay Description
Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...


Bioorg Med Chem 23: 6855-68 (2015)

More data for this
Ligand-Target Pair