BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-serine O-palmitoleoyltransferase porcupine' and Ligand = 'BDBM50133868'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-serine O-palmitoleoyltransferase porcupine


(Homo sapiens)
BDBM50133868
PNG
(CHEMBL3633804)
Show SMILES Cn1c2nc3CC[C@@H](CC(=O)Nc4ccc(nn4)-c4ccccc4)n3c2c(=O)n(C)c1=O
Show InChI InChI=1/C22H21N7O3/c1-27-20-19(21(31)28(2)22(27)32)29-14(8-11-17(29)24-20)12-18(30)23-16-10-9-15(25-26-16)13-6-4-3-5-7-13/h3-7,9-10,14H,8,11-12H2,1-2H3,(H,23,26,30)/t14-/s2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 5n/an/an/an/an/an/a



Experimental Therapeutics Centre

Curated by ChEMBL


Assay Description
Inhibition of porcupine in human HEK293 cells by STF reporter assay


Bioorg Med Chem Lett 25: 5472-6 (2015)

More data for this
Ligand-Target Pair