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Found 4 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM238263'
TargetProthrombin(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM238263(US10336741, Example 88 | US10882855, Example 88 | ...)
Affinity DataIC50:  5.70E+4nMAssay Description:Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM238263(US10336741, Example 88 | US10882855, Example 88 | ...)
Affinity DataIC50:  5.70E+4nMAssay Description:Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM238263(US10336741, Example 88 | US10882855, Example 88 | ...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibitory activities of compounds of the present invention against factor XIa, Xa, XIIa, IXa, VIIa, plasma kallikrein or thrombin were evaluated usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM238263(US10336741, Example 88 | US10882855, Example 88 | ...)
Affinity DataIC50:  5.70E+4nMAssay Description:Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent